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Review: tissue adhesives are as effective as standard wound closure for cosmetic outcomes of traumatic lacerations

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QUESTION: Are tissue adhesives (TAs) as effective as standard wound closure (SWC) for traumatic lacerations in children and adults? Are some TAs better than others?

Data sources

Published and unpublished studies in any language were identified by searching the Cochrane Controlled Trials Register (CD ROM 2001 Issue 4), the Cochrane Wounds Group Specialized Trials Register (November 2001), Medline (1966 to October 1, 2001), and EMBASE/Excerpta Medica (1988 to September 1, 2001); reviewing the bibliographies of retrieved articles; and by contacting study authors and manufacturers of TAs.

Study selection

Randomised controlled trials were included if they compared TAs with SWC (ie, sutures, staples, or adhesive strips) or compared 2 different TAs for acute, linear lacerations that were <12 hours old resulting from blunt or sharp trauma in patients seen in an emergency department (ED) or primary care setting. Exclusion criteria were stellate lacerations, puncture …

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  • For correspondence: Dr K Farion, Emergency Medicine, Departments of Pediatrics and Medicine, University of Ottawa, Children’s Hospital of Eastern Ontario, Ottawa, Ontario, Canada. farion{at}

  • Source of funding: Alberta Heritage Foundation for Medical Research, Canada