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  • Thromboprophylaxis with low dose unfractionated heparin plus compression stockings reduces thromboembolic complications of colorectal surgery

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Thromboprophylaxis with low dose unfractionated heparin plus compression stockings reduces thromboembolic complications of colorectal surgery

https://doi.org/10.1136/ebn.5.2.50

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    Wille-Jørgensen P, Rasmussen MS, Andersen BR, et al. Heparins and mechanical methods for thromboprophylaxis in colorectal surgery. Cochrane Database Syst Rev 2001;(4):CD001217 (latest version May 26 2001).

    QUESTION: In patients having colorectal surgery, what is the effectiveness of prophylactic methods using heparin and mechanical methods on reducing postoperative thromboembolism (TE)?

    Data sources

    Studies were identified by searching Medline, EMBASE/Excerpta Medica, and the Cochrane Library (1970 to May 2000). Meeting abstracts and reference lists of reviews were handsearched.

    Study selection

    Studies were selected if they were randomised controlled trials (RCTs) or controlled clinical trials; compared prophylactic interventions using heparins or mechanical methods or both with each other or placebo; included patients >18 years of age having major colorectal surgery; diagnosed TE objectively using ascending venography, the 125-I-fibrinogen uptake test, ultrasound or Doppler methods, pulmonary scintigraphy, or autopsy; and reported start and end times of …

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    Footnotes

    • Source of funding: in part, Copenhagen Hospital Corporation.

    • For correspondence: Dr P Wille-Jørgensen, Department of Surgical Gastroenterology K, Bispebjerg Hospital, Copenhagen NV, Denmark. peerwille{at}vip.cybercity.dk