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  • Cognitive behavioural therapy plus medical management reduced depression and joint inflammation in rheumatoid arthritis

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Cognitive behavioural therapy plus medical management reduced depression and joint inflammation in rheumatoid arthritis

http://dx.doi.org/10.1136/ebn.4.4.120

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    Sharpe L, Sensky T, Timberlake N, et al.A blind, randomized, controlled trial of cognitive-behavioural intervention for patients with recent onset rheumatoid arthritis: preventing psychological and physical morbidity.Pain2001 Jan;89:275–83OpenUrlCrossRefPubMedWeb of Science

    QUESTION: Does the addition of cognitive behavioural therapy (CBT) to medical management relieve symptoms and reduce disability and psychological distress in patients with recent onset rheumatoid arthritis (RA)?

    Design

    Randomised {allocation concealed}*, blinded (outcome assessor), controlled trial with 6 months of follow up.

    Setting

    Rheumatology clinics at 3 hospitals in or near London, UK.

    Patients

    56 patients who were 18–75 years of age, had had definite or classic RA for <2 years, and tested seropositive for RA. Exclusion criteria were history of mental illness or alcohol or drug abuse, or insufficient fluency in English. Follow up was 80% (mean age 55 y, 71% women, mean …

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    Footnotes

    • ↵* Information provided by author.

    • Source of funding: North Thames Regional Research and Development Programme.

    • For correspondence: Dr L Sharpe, Department of Psychology, Clinical Studies Unit F12, University of Sydney, New South Wales 2006, Australia. Fax +61 2 9351 7328.

    • A modified version of this abstract appears in Evidence-Based Mental Health.