Article Text

Download PDFPDF

Continuous topical heat was as effective as ibuprofen for dysmenorrhoea

Statistics from

OpenUrlCrossRefPubMedWeb of Science

QUESTION: Is continuous, low level, topical heat as effective as oral ibuprofen for dysmenorrhoea (menstrual pain)?


Randomised {allocation concealed}*, blinded {patients, clinicians, and outcome assessors}*, controlled, 2 × 2 factorial trial with follow up over 2 days of treatment.


Texas, USA.


84 non-pregnant women who were ≥18 years (age range 21–50 y) and who predictably had moderate or greater menstrual pain (4 of previous 6 cycles), a history and physical examination consistent with primary dysmenorrhoea, regular menstrual cycles, pain relief from over the counter analgesics, and were using reliable contraception. Exclusion criteria were cutaneous lesions involving the abdominal wall, microvascular disease (including diabetes), known or suspected drug or alcohol abuse, known or suspected contraindication to oral ibuprofen, and recent pregnancy. 79 women (94%) were included in the efficacy analysis.


Women were allocated to 1 of 4 treatment groups, each of which comprised …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.