Article Text

Download PDFPDF
Continuous topical heat was as effective as ibuprofen for dysmenorrhoea

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

OpenUrlCrossRefPubMedWeb of Science

QUESTION: Is continuous, low level, topical heat as effective as oral ibuprofen for dysmenorrhoea (menstrual pain)?


Randomised {allocation concealed}*, blinded {patients, clinicians, and outcome assessors}*, controlled, 2 × 2 factorial trial with follow up over 2 days of treatment.


Texas, USA.


84 non-pregnant women who were ≥18 years (age range 21–50 y) and who predictably had moderate or greater menstrual pain (4 of previous 6 cycles), a history and physical examination consistent with primary dysmenorrhoea, regular menstrual cycles, pain relief from over the counter analgesics, and were using reliable contraception. Exclusion criteria were cutaneous lesions involving the abdominal wall, microvascular disease (including diabetes), known or suspected drug or alcohol abuse, known or suspected contraindication to oral ibuprofen, and recent pregnancy. 79 women (94%) were included in the efficacy analysis.


Women were allocated to 1 of 4 treatment groups, each of which comprised …

View Full Text


  • * Information provided by author.

  • Source of funding: Procter and Gamble Company supplied study devices and materials.

  • For correspondence: Dr R P Smith, Department of Obstetrics and Gynecology, Truman Medical Center, 2301 Holmes Street, Kansas City, MO 64108, USA. Fax +1 816 556 3556.