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  • Developmental outcomes did not differ for early or delayed tympanostomy tube insertion in young children with otitis media

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Developmental outcomes did not differ for early or delayed tympanostomy tube insertion in young children with otitis media

https://doi.org/10.1136/ebn.4.4.108

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    Paradise JL, Feldman HM, Campbell TF, et al. Effect of early or delayed insertion of tympanostomy tubes for persistent otitis media on developmental outcomes at the age of three years.N Engl J Med2001 Apr 19;344:1179–87OpenUrlCrossRefPubMedWeb of Science

    QUESTION: In young children with persistent otitis media with effusion, does prompt insertion of tympanostomy tubes protect against or minimise subsequent developmental impairment at 3 years of age compared with delayed insertion?

    Design

    Randomised (allocation concealed), blinded (outcome assessors), controlled trial with follow up to 3 years of age.

    Setting

    2 hospitals and 6 private paediatric group practices in Pittsburgh, Pennsylvania, USA.

    Patients

    Of 6350 children enrolled by age 2 months, 429 children (mean age 15 mo, 57% boys) in …

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    Footnotes

    • Sources of funding: National Institute for Child Health and Human Development; Agency for Healthcare Research and Quality; gifts from SmithKline Beecham Laboratories and Pfizer.

    • For correspondence: Dr J L Paradise, Children's Hospital of Pittsburgh, 3705 Fifth Ave, Pittsburgh, PA 15213-2538, USA. Fax +1 412 692 8012.

    • A modified version of this abstract appears in Evidence-Based Medicine.