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Amethocaine gel reduced pain during venipuncture in newborn infants

https://doi.org/10.1136/ebn.4.3.73

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    Jain A, Rutter N.Does topical amethocaine gel reduce the pain of venepuncture in newborn infants? A randomised double blind controlled trial.Arch Dis Child Fetal Neonatal Ed2000 Nov;83:F207–10OpenUrlAbstract/FREE Full Text

    QUESTION: Does topical amethocaine gel reduce pain during venipuncture in newborn infants?

    Design

    Randomised (allocation concealed), blinded (patients, clinicians, outcome assessors), placebo controlled trial with follow up immediately after the procedure.

    Setting

    Postnatal wards and the neonatal intensive care unit at the Nottingham City Hospital, Nottingham, UK.

    Patients

    40 newborn infants (median age 7 d, median gestational age 33 wks) who required venipuncture as part of their routine care. Infants who were unwell, ventilated, or sedated were excluded. Follow up was 98%.

    Intervention

    20 infants were allocated to 1.5 g of 4% amethocaine gel and 20 were …

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    Footnotes

    • Source of funding: Higher Education Funding Council.

    • For correspondence: Dr A Jain, Department of Neonatal Medicine, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK. Fax +44 (0)115 962 7926.