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QUESTION: Does topical amethocaine gel reduce pain during venipuncture in newborn infants?
Randomised (allocation concealed), blinded (patients, clinicians, outcome assessors), placebo controlled trial with follow up immediately after the procedure.
Postnatal wards and the neonatal intensive care unit at the Nottingham City Hospital, Nottingham, UK.
40 newborn infants (median age 7 d, median gestational age 33 wks) who required venipuncture as part of their routine care. Infants who were unwell, ventilated, or sedated were excluded. Follow up was 98%.
20 infants were allocated to 1.5 g of 4% amethocaine gel and 20 were …
Source of funding: Higher Education Funding Council.
For correspondence: Dr A Jain, Department of Neonatal Medicine, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK. Fax +44 (0)115 962 7926.