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  • Children who were exposed to antenatal corticosteroids and had birth weights ⩽1500 g did not have adverse growth, cognitive, or lung function outcomes at age 14 years

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Children who were exposed to antenatal corticosteroids and had birth weights ⩽1500 g did not have adverse growth, cognitive, or lung function outcomes at age 14 years

https://doi.org/10.1136/ebn.4.2.56

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    Doyle LW, Ford GW, Rickards AL, et al. Antenatal corticosteroids and outcome at 14 years of age in children with birth weight less than 1501 grams.Pediatrics2000 Jul;106:e2.OpenUrlAbstract/FREE Full Text

    QUESTION: Are children who were exposed to antenatal corticosteroids and had birth weights ⩽1500 g at increased risk of adverse growth, cognitive, and lung function outcomes at age 14 years?

    Design

    Cohort study.

    Setting

    A hospital in Melbourne, Australia.

    Participants

    154 consecutive infants (mean gestational age 29.4 wks, 53% boys) with birth weights ⩽1500 g who survived to age 14 years, corrected for prematurity. 130 children (84%) were assessed at age 14 years.

    Assessment of risk factors

    78 mothers (51%) had received 1 course of antenatal corticosteroids (betamethasone) to accelerate fetal lung maturation, and 76 (49%) had not received any antenatal corticosteroids.

    Main outcome measures

    Height, weight, and head circumference (z scores for appropriate age and sex, relative to the British …

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    Footnotes

    • Source of funding: in part, the Royal Women's Hospital Research Foundation.

    • For correspondence: Dr L W Doyle, Division of Newborn Services, Royal Women's Hospital, 132 Grattan Street, Carlton, Victoria 3053, Australia.