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Contamination of urine specimens from women with acute dysuria did not differ with collection technique

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QUESTION: Does contamination of urine specimens from women with acute dysuria differ with collection technique (midstream, midstream plus vaginal tampon, or no cleansing)?


Randomised {allocation not concealed}*, blinded (outcome assessors), controlled trial.


An outpatient clinic at Rutgers University, New Jersey, USA.


242 consecutive women (mean age 21 y), mostly undergraduates, with symptoms suggestive of cystitis. Exclusion criteria were antibiotic use or urethral instrumentation in the previous 7 days, or known urological abnormality or nephrolithiasis. Follow up was complete.


84 women were allocated to midstream collection and were instructed to cleanse the perineum with a bactericidal wipe by wiping from front to rear, to spread the labia, discard the first urine …

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  • Source of funding: no external funding.

  • For correspondence: Dr E I Lifshitz, Rutgers University Health Services, 110 Hospital Road, Piscataway, NJ 08854, USA. Fax +1 732 445 3725.

  • A modified version of this abstract appears in Evidence-Based Medicine.

  • * Information provided by author.