You are here

Article Text

Article menu
Download PDFPDF
Causation
Review: postmenopausal hormone replacement therapy is associated with a decreased risk of colorectal cancer

https://doi.org/10.1136/ebn.3.2.58

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Grodstein F, Newcomb PA, Stampfer MJ.Postmenopausal hormone therapy and the risk of colorectal cancer: a review and meta-analysis.Am J Med1999 May;106:574–82OpenUrlCrossRefPubMedWeb of Science

    QUESTION: Is postmenopausal hormone replacement therapy associated with a decreased risk of colorectal cancer in women?

    Data sources

    English language studies were identified by searching Medline (1966 to September 1998) using the subject headings for colorectal, colon, and rectal neoplasms or the textwords “colorectal, colon, and rectal cancer” and the subject headings “estrogen, estrogen replacement therapy” or the textwords “hormone replacement therapy, postmenopausal hormones, or non contraceptive hormones”. Bibliographies were also reviewed.

    Study selection

    Studies were selected if they provided estimates of the risk of colon or rectal cancer in relation to postmenopausal hormone use.

    Data extraction

    Data were extracted on study design, cases of colon cancer, categories of hormone use (ever use, current use, and duration of use), odds …

    View Full Text

    Footnotes

    • Source of funding: National Institutes of Health.

    • For correspondence: Dr F Grodstein, Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA. Fax +1 617 525 2008.