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Causation
Diastolic blood pressure and weight gain predicted future risk of hypertension

https://doi.org/10.1136/ebn.3.1.26

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    Bakx JC, van den Hoogen HJM, van den Bosch WJHM, et al. Development of blood pressure and the incidence of hypertension in men and women over an 18-year period: results of the Nijmegen Cohort Study.J Clin Epidemiol1999 Jun;52:531–8.OpenUrlCrossRefPubMedWeb of Science

    QUESTION: Does diastolic blood pressure (BP) or other cardiovascular risk factors predict the future onset of hypertension in people who are not undergoing hypertension treatment at baseline?

    Design

    Prospective cohort study of men and women in the Nijmegen Cohort Study with 18 years of follow up.

    Setting

    6 general practices in Nijmegen, the Netherlands.

    Participants

    2238 men and women between 20 and 50 years of age (mean age 35 y, 52% men, 100% white). Participants who …

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    Footnotes

    • Source of funding: The Netherlands Heart Foundation.

    • For correspondence: Dr J C Bakx, Department of General Practice, University of Nijmegen, 229 HSV, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Fax +31 24 354 1862.

    • A modified version of this abstract also appears in Evidence-Based Medicine and ACP Journal Club.