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Managing multimorbidity in midlife may reduce the risk of developing dementia as we age
  1. Valentina Spedale1,2,
  2. Paolo Mazzola1,3
  1. 1 School of Medicine and Surgery, Università degli Studi di Milano-Bicocca, Monza, Italy
  2. 2 Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy
  3. 3 Acute Geriatrics Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy
  1. Correspondence to Professor Paolo Mazzola, School of Medicine and Surgery, Universita degli Studi di Milano-Bicocca, Monza, Italy; paolo.mazzola{at}unimib.it

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Commentary on: Veronese N, Koyanagi A, Dominguez LJ, et al. Multimorbidity increases the risk of dementia: a 15 year follow-up of the SHARE study. Age Ageing 2023;52(4):afad052. doi: 10.1093/ageing/afad052.

Implications for practice and research

  • Stroke, hypercholesterolaemia, diabetes, and osteoporosis are modifiable risk factors for the development of dementia.

  • People with multimorbidity should be encouraged to have regular cognitive assessments starting in middle age. Meanwhile, healthy lifestyles should be promoted from childhood.

Context

The world population is ageing significantly, with a projected 2 billion people over the age of 65 by 2050.1 A major consequence of population ageing is the increasing prevalence of dementia, which raises significantly after age 65 and is considered a global public health priority by WHO. A further consequence of ageing is the increase in multimorbidity (coexistence of ≥2 chronic conditions), which is particularly …

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Footnotes

  • X @paolinomj

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.