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Literature suggests gaps in evidence-based PRN medication practices in acute mental healthcare
  1. Kirsi Hipp
  1. School of Wellbeing, Häme University of Applied Sciences, Hämeenlinna, Finland
  1. Correspondence to Dr Kirsi Hipp, School of Wellbeing, Häme University of Applied Sciences, Hämeenlinna FI-13100, Finland; kirsi.hipp{at}

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Commentary on: Wong S, Müller A. Nurses' use of pro re nata medication in adult acute mental healthcare settings: An integrative review. Int J Ment Health Nurs. 2023 Apr 6. doi: 10.1111/inm.13148. Epub ahead of print.

Implications for practice and research

  • This literature review provides synthesised evidence to evaluate and improve the clinical practice of pro re nata (PRN) medication in mental healthcare organisations.

  • Further research focused on exploring grey literature would offer additional perspectives and broaden the current clinical practices of PRN utilisation.


PRN refers to unscheduled medication used to manage acute symptoms. PRN is commonly used in mental healthcare, but literature suggests that its use is not always based on evidence. This review offers knowledge for developing evidence-based PRN practice. The nurses play a crucial role in PRN administration, including assessing patients’ needs …

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  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.