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Cardiomyopathy and pregnancy: a high-risk combination
  1. Despoina Ntiloudi1,
  2. George Giannakoulas2
  1. 1 Cardiology Department, Tzaneio General Hospital of Piraeus, Piraeus, Greece
  2. 2 AHEPA University Hospital, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece
  1. Correspondence to Dr George Giannakoulas, University General Hospital of Thessaloniki AHEPA, Thessaloniki 54621, Greece; g.giannakoulas{at}

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Commentary on: Eggleton EJ, McMurrugh KJ, Aiken CE. Maternal pregnancy outcomes in women with cardiomyopathy: a systematic review and meta-analysis. Am J Obstet Gynecol. 2022 Oct;227(4):582–592. doi: 10.1016/j.ajog.2022.05.039. Epub 2022 May 2021

Implications for practice and research

  • Pregnant patients with cardiomyopathy have a risk of complications and should be advised accordingly.

  • Prospective data focusing on pregnancy outcomes in patients with various subtypes of cardiomyopathies are warranted to ensure proper counselling of these patients.


Haemodynamic changes, especially blood volume, heart rate and cardiac output augmentation, during pregnancy can exacerbate symptoms in patients with cardiomyopathy or unmask a preexisting asymptomatic condition.1 Peripartum cardiomyopathy, which also belongs in the cardiomyopathy group, presents with left ventricular (LV) dysfunction towards the end of pregnancy and in the postpartum period, when no other cause of heart …

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  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.