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Women's health and midwifery
Menstrual cycle changes after COVID-19 vaccination or infection: not two sides of the same coin
  1. Antonio Simone Laganà1,
  2. David Lukanovič2,
  3. Marco Noventa3,
  4. Chrysoula Margioula-Siarkou4,
  5. Sanja Terzic5,
  6. Vito Chiantera1
  1. 1 Unit of Gynecologic Oncology, ARNAS "Civico – Di Cristina – Benfratelli", Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy
  2. 2 Department of Gynecology, Division of Gynecology and Obstetrics, Ljubljana Medical Center, Ljubljana, Slovenia
  3. 3 Department of Women’s and Children’s Health, Clinic of Gynecology and Obstetrics, University of Padua, Padua, Italy
  4. 4 2nd Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
  5. 5 Department of Medicine, School of Medicine, Nazarbayev University, Astana, Kazakhstan
  1. Correspondence to Dr Antonio Simone Laganà, Unit of Gynecologic Oncology, ARNAS "Civico – Di Cristina – Benfratelli", Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy; antoniosimone.lagana{at}unipa.it

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Commentary on: Wang S, Mortazavi J, Hart JE, et al. A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics. Am J Obstet Gynecol. 2022 Jul 13;227(5):739.e1–739.e11. doi: 10.1016/j.ajog.2022.07.003. Epub ahead of print.

Implications for practice and research

  • Physicians should inform that COVID-19 vaccination is associated with an increased risk of a longer menstrual period during the first 6 months postvaccination, especially among women who had irregular, short or long prevaccination menstruation.

  • Future long-term follow-ups should evaluate menstrual cycle patterns in reproductive age and postmenopausal women who underwent COVID-19 vaccination.

Context

The COVID-19 pandemic has significantly shaped several elements of our lives, including healthcare policy.1 Several governments solicited campaigns to increase the vaccination rate of healthcare providers, fragile patients and the general population …

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Footnotes

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.