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Nursing issues
Sleep deprivation provokes aberrant dynamic brain activity and memory decline among night shift nurses
  1. Valentina Alfonsi
  1. Department of Psychology, University of Rome La Sapienza, Roma, Lazio, Italy
  1. Correspondence to Dr Valentina Alfonsi, University of Rome La Sapienza Department of Psychology, Roma, Lazio, Italy; valentina.alfonsi{at}

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Commentary on: Yan FX, Lin JL, Lin JH, et al. Altered dynamic brain activity and its association with memory decline after night shift-related sleep deprivation in nurses. J Clin Nurs. 2022 Sep 8. doi: 10.1111/jocn.16515. Epub ahead of print.

Implications for practice and research

  • An in-depth understanding of the adverse consequences of night shift-related sleep deprivation sheds light on possible countermeasures.

  • Future studies should investigate the predictive role of the identified neurobiological markers of sleep deprivation on memory decline.


There is mounting evidence that night shift work significantly impacts on both circadian and homeostatic sleep processes in healthcare workers,1 resulting in dramatic sleep loss. Beyond the well-known consequences on physical and mental health,2 several studies described an impairment of cognitive function following night shift-related sleep deprivation (SD) in nurses.3. However, the neural substrates underlying memory dysfunction …

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  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.