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Commentary on: Falcaro M, Castañon A, Ndlela B, et al. The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade three cervical intraepithelial neoplasia incidence: a register-based observational study. Lancet 2021; Dec 4;398 (10316):2084–2092.
Implications for practice and research
The high burden of cervical cancer in low-income and middle-income countries highlights the need for early prevention.
Research on the beneficial effects of papillomavirus vaccination in low-income and middle-income countries is a priority.
Context
International agency for research on cancer estimated that nearly 604 000 women were diagnosed with cervical cancer and about 342 000 women died from the disease worldwide in 2020.1 The main cause of cervical cancer is persistent infection with high-risk oncogenic strains of human papillomavirus (HPV) including 16 and 18. Vaccination against high-risk HPV types, …
Footnotes
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.