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Commentary on: Jennings ELM, Murphy KD, Gallagher P, O'Mahony D. In-hospital adverse drug reactions in older adults; prevalence, presentation and associated drugs-a systematic review and meta-analysis. Age Ageing. 2020;49(6):948–958. doi:10.1093/ageing/afaa188
Implications for practice and research
Adverse drug reactions (ADRs) are highly prevalent in hospitalised older patients, caused by commonly used drugs and present as clinical scenarios seen in daily clinical practice.
Future research should focus on standardisation of ADR ascertainment and assessment, hopefully leading to reporting of patient-related health outcomes.
WHO defines an adverse drug reaction (ADR) as a response to a medicine which is noxious and unintended, and which occurs at doses normally used in man and adverse drug event or experience (ADEs) as any untoward medical occurrence that may present during treatment with a medicine but which does not necessarily have a causal relationship with this treatment.1 ADRs and ADEs represent a significant proportion of older adult acute …
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.