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Nursing issues
Non-infectious complications of peripheral venous catheters are common
  1. Mahendar Vyasabattu,
  2. Pradeep Yarra
  1. Department of Internal Medicine, University of Kentucky Medical Center, Lexington, Kentucky, USA
  1. Correspondence to Dr Pradeep Yarra, Internal Medicine, University of Kentucky, Lexington, KY 40506, USA; pya227{at}

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Commentary on: Marsh N, Webster J, Ullman AJ, et al. Peripheral intravenous catheter non-infectious complications in adults: A systematic review and meta-analysis. J Adv Nurs 2020 Dec;76(12):3346–3362. DOI: 10.1111/jan.14565

Implications for practice and research

  • Peripheral venous catheters are associated with non-infectious complications such as phlebitis and infiltration/extravasation.

  • Future research and guidelines should focus on identifying evidence-based interventions to reduce the incidence of these complications


Peripheral intravenous catheters (PIVCs) are the most commonly used vascular access devices among hospitalised patients, but little is known about the impact of non-infectious complications associated with them. Current guidelines from multiple nations, including England and USA, focus primarily on infection prevention.1 These guidelines lacked a concerted effort to recognise and address non-infectious complications. Failure of PIVCs lead to extra burden on healthcare resources, delay in treatments and increased the need for central line catheters.2 …

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  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.