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Adult nursing
Efficacy of non-pharmacological treatments of fatigue in individuals with end-stage disease
  1. Terri Kean
  1. Faculty of Nursing, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada
  1. Correspondence to Professor Terri Kean, Faculty of Nursing, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada; tkean1965{at}

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Commentary on: Mochamat, Cuhls H, Sellin J, et al. Fatigue in advanced disease associated with palliative care: a systematic review of non-pharmacological treatments. Palliat Med 2021; 35:697–709. doi: 10.1177/02692163211000628

Implications for practice and research

  • Well documented among patients with cancer, fatigue can also be a debilitating symptom among individuals living with non-cancer conditions.

  • Research to examine the efficacy of non-pharmacological treatments for fatigue in chronically ill patients with non-cancer conditions may provide insight into assessment and management strategies that improve quality of life.


Fatigue is reported as the principal concern in 5%–10% of primary care visits and a further 10% of family practice consultations. In the broader community, 5%–20% of the general population experience fatigue and almost half report its presence 1 year later.1 The majority of individuals with cancer experience fatigue (59%–100%), depending on disease progression and/or treatment regimes.2 While 80% of individuals living with fatigue rate it as significant to …

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  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.