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Commentary on: Feigelson HS, Caan B, Weinmann S, et al. Bariatric surgery is associated with reduced risk of breast cancer in both premenopausal and postmenopausal women. Ann Surg 2019 https://doi.org/0.1097/SLA.0000000000003331. [Epub ahead of print 13 Apr 2019].
Implications for practice and research
Preliminary evidence suggests that bariatric surgery reduces the risk of postmenopausal oestrogen-positive and premenopausal oestrogen-negative breast cancer.
International, prospective, longitudinal studies using power calculations are required.
Context
Obesity influences the development, prognosis and mortality rates of many types of cancer including that of the breast.1 Research correlates weight gain in adulthood with an increased risk of breast cancer.2 The International Agency for Research on Cancer contends that the relationship between intentional weight loss and cancer risk is yet to be determined.1 Winder and colleagues3 suggest …
Footnotes
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Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.