Article Text

Download PDFPDF
Adult nursing
Harm-benefit analysis: treatment of mild hypertension in low-risk individuals
  1. Terri Kean
  1. Faculty of Nursing, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada
  1. Correspondence to Professor Terri Kean, Faculty of Nursing, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada; tkean1965{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Commentary on: Sheppard et al. Benefits and harms of antihypertensive treatment in low-risk patients with mild hypertension. JAMA Internal Medicine

Implications for practice and research

  • A risk-based approach that includes tailored targets and comorbidity may be optimal in the management of hypertension.1

  • Research to examine risk-over-time as a prognostic indicator in the development of cardiovascular disease (CVD) in low-risk patients may provide greater insight into the benefit of treating mild hypertension in these individuals.1


Hypertension, a growing global burden, affects one-quarter of the world’s population.1–3 Uncontrolled hypertension can lead to life-threatening sequelae, decreased quality of life and increased expenditures by health systems.1–3 Evidence-based guidelines, a mainstay of modern practice, feature prominently in clinical decision-making.3 4 Yet, some guidelines can spur controversy.

Sheppard et al conducted a harm-benefit analysis of …

View Full Text


  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.