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Question In people with bulimia nervosa, how do medication and cognitive behaviour therapy (CBT) compare in controlling binge and purge frequency, depression, and eating attitudes?
Studies were identified by searching Medline (1966–98) and PsycLIT (1974–98) using the terms bulimia, bulimia nervosa, treatment outcome, clinical trial, and double blind; references of studies were reviewed; and journals specific to eating disorders were searched for the previous 8 years.
Studies were selected if they were randomised controlled trials of patients diagnosed with bulimia nervosa according to DSM-III criteria. Studies of pharmacological interventions had to be double blind and placebo controlled. Psychosocial studies could involve CBT, behaviour therapy, or exposure and response prevention, but for the purposes of this …
Source of funding: no external funding.
For correspondence: Dr M L Whittal, Vancouver Hospital and Health Sciences Centre—UBC site, 2211 Wesbrook Mall, Vancouver, BC V6T 2B5, Canada. Fax +1 604 822 7452.
A modified version of this abstract appears in Evidence-Based Mental Health and Evidence-Based Medicine.