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Early opportunistic screening was cost effective in young adults with type 2 diabetes

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Question Is opportunistic screening for early detection and treatment of type 2 diabetes cost effective?


Cost effectiveness analysis using a semi-Markov Monte Carlo simulation model.


A single payer healthcare system in the US.


A hypothetical cohort of people ≥25 years of age without clinically diagnosed diabetes was used (screening module). For 10 000 individuals with diabetes in this cohort, the model simulated the development and progression of major complications of the disease (disease progression module).


People in the screening module were assigned to either 1 time opportunistic screening for diabetes or to current clinical practice. Screening was done during a routine physician visit. Diabetes was defined as a fasting plasma glucose >6.1 mmol/l (110 mg/dl) and confirmed by an oral glucose …

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  • Source of funding: not stated.

  • For correspondence: Dr M M Engelgau, Division of Diabetes Translation, Mailstop K-10, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341–3724, USA. Fax +1 770 488 5966.