You are here

Article Text

Article menu
Download PDFPDF
Causation
Multiple attempts to stop smoking, even with relapses, reduced loss of pulmonary function

https://doi.org/10.1136/ebn.2.3.90

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Murray RP, Anthonisen NR, Connett JE, et al for the Lung Health Study Research Group. Effects of multiple attempts to quit smoking and relapses to smoking on pulmonary function.J Clin Epidemiol1998 Dec; 51:1317–26.OpenUrlCrossRefPubMedWeb of Science

    Question What are the effects of multiple failed attempts to stop smoking on pulmonary function of adults?

    Design

    Retrospective analysis of a cohort of participants involved in a randomised controlled trial (Lung Health Study), with annual follow up for 5 years.

    Setting

    10 clinical centres in North America.*

    Participants

    5887 adults aged 35–60 years, who smoked and had evidence of early chronic obstructive pulmonary disease (ie, had an FEV1/FVC [forced expiratory volume at 1 sec/forced vital capacity] interval of ≤70%, and an FEV1 of 55–90% of predicted normal).

    Assessment of risk factors

    Smoking status was assessed at baseline and at 5 annual visits thereafter. Participant reports of abstinence were confirmed by salivary cotinine concentrations (<20 ng/ml) or if nicotine substitution therapy was used, by CO concentrations (<10 ppm in end tidal …

    View Full Text