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Soy milk decreased chronic constipation in young children

https://doi.org/10.1136/ebn.2.3.76

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    Iacono G, Cavataio F, Montalto G, et al. Intolerance of cow's milk and chronic constipation in children.N Engl J Med 1998 Oct 15; 339:1100–4.OpenUrlCrossRefPubMedWeb of Science

    Question Does soy milk increase stool frequency in young children who have chronic constipation and are being given cows' milk?

    Design

    Randomised, controlled, double blind, crossover trial.

    Setting

    A paediatric gastroenterology clinic at a university hospital in Italy.

    Patients

    65 children <6 years of age (mean age 34.6 mo, 55% girls) who were referred for chronic constipation (chronic fecal retention of 1 bowel movement every 3–15 d often associated with abdominal symptoms). Exclusion criteria were anatomical causes of constipation, constipation caused by another disorder, previous anal surgery, and use of medications associated with constipation. All children were being fed cows' milk, dairy products, or commercial formulas derived from cows' milk. All had unsuccessful treatment with laxatives. Follow up was complete.

    Intervention

    Children who were <15 months old were given formula (based on cows' …

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    Footnotes

    • Source of funding: none stated.

    • For correspondence: Dr A Carroccio, University of Palermo, via Coffaro 25, I-90124 Palermo, Italy. Fax +39 (0)91 6552936.