Article Text

Download PDFPDF
Calcium reduced PMS symptoms during the luteal phase of the menstrual cycle

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

OpenUrlCrossRefPubMedWeb of Science

Question Can calcium supplementation reduce the symptoms that occur during the luteal and menstrual phases of the menstrual cycle in women with premenstrual syndrome (PMS)?


Randomised, double blind, placebo controlled trial.


12 outpatient health centres in the US.


497 healthy, premenopausal women aged 18–45 years (mean age 33 y, 80% white) who had regular menstrual cycles, a history of cyclically recurring PMS, PMS symptoms of at least moderate severity confirmed by a validated PMS diary for ≥2 menstrual cycles, and ≥1 of the following: mood swings, depression, tension, anxiety, anger, or crying spells. Exclusion criteria were use of analgesics, digitalis, bile acid resin binders, or levonorgestrel; chronic or excessive use of calcium based antacids or calcium supplements; renal disease or colic; …

View Full Text


  • Source of funding: SmithKline Beecham Consumer Healthcare.

  • For correspondence: Dr S Thys-Jacobs, St Luke's-Roosevelt Hospital Center, 425 West 59th Street, Suite 9C, New York, NY 10019, USA. Fax +1 212 523 8102.