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Cohort study
Hypovitaminosis D predicts more rapid and severe cognitive deterioration in ethnically diverse older adults with and without dementia
  1. Frédéric Noublanche,
  2. Cédric Annweiler
  1. Department of Neuroscience, University Hospital of Angers, Angers, France
  1. Correspondence to : Professor Cédric Annweiler, Department of Neuroscience, Angers University Hospital, University Memory Clinic, University of Angers, UPRES EA 4638, UNAM, Angers 49933, France; CeAnnweiler{at}

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Commentary on: OpenUrlCrossRefPubMed

Implications for practice and research

  • Hypovitaminosis D precedes and predicts incident declines in episodic memory and executive function in older adults with and without baseline dementia.

  • This finding encourages testing the efficacy of vitamin D supplementation to slow down, prevent or even improve cognitive decline.

  • These findings should encourage clinicians to correct hypovitaminosis D in elderly patients.


Hypovitaminosis D is a rule rather than an exception in older adults, with a prevalence of up to 90% according to the definition used.1 There is a growing body of evidence linking vitamin D to non-skeletal targets, including brain health and function.2 The …

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  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.