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Quantitative study—other
Movement pain, resting pain and depression prior to total knee replacement predict postoperative pain
  1. James A Browne
  1. Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, USA
  1. Correspondence to : Dr James A Browne
    Department of Orthopaedic Surgery, University of Virginia, PO Box 800159, Charlottesville, VA 22908, USA; jab8hd{at}

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Implications for practice and research

  • Younger patients with higher preoperative pain and depression are more likely to have higher pain on postoperative day 2 following total knee arthroplasty.

  • Cutaneous pain sensitivity correlates with postoperative knee movement pain but not rest pain, which suggests different underlying pain mechanisms.

  • Future research should investigate whether presurgical intervention on pain and psychological factors can improve postoperative pain and long-term outcomes following total knee arthroplasty (TKA).


TKA is generally regarded as a highly successful procedure to improve pain and function in patients with advanced degenerative joint disease. Perioperative pain management remains a major concern for patients contemplating TKA and residual pain has been associated with dissatisfaction and poor outcome. This study aims to identify …

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  • Competing interests None.