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Implications for practice and research
■ Data from this study support the assertion that the use of non-steroidal anti-inflammatory drugs (NSAIDs) during pregnancy is associated with increased risk of spontaneous abortion and should, therefore, be used with caution.
■ However, other factors such as socio-economic status and co-existing illnesses may have biased these results.
■ Further research is needed to explore the effect of taking NSAIDs during pregnancy and the other factors identified.
■ Future research should include data relating to the use of both prescription and over-the-counter NSAIDs.
NSAIDs are one of the commonest classes of drugs taken by pregnant …
Competing interests None.
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