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Systematic review
A review of long-term effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol and triglyceride
  1. Maureen McCormick Covelli
  1. College of Nursing, University of Central Florida, Orlando, Florida, USA
  1. Correspondence to Maureen McCormick Covelli
    College of Nursing, University of Central Florida, 12201 Research Rarkway, Suite 300, Orlando, FL 32826, USA; Maureen.Covelli{at}

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Implications for practice and research

  • Low sodium diet in normotensive Caucasians showed less than 1% decrease in systolic blood pressure (SBP) and 3.5% decrease in hypertensive Caucasian populations.

  • Further controlled studies are needed on the effect of sodium reduction among Blacks and Asians.

  • Sodium reduction diet resulted in significant increase in lipids (plasma cholesterol and triglycerides) and hormones (renin, aldosterone, and catecholamine).

  • Research on long-term hormonal and lipid effects of sodium restriction diets is needed.


Low sodium diets have been a major hypertension prevention and treatment theme. Evidence supporting interventions of reduced sodium intake as a generalised hypertension prophylaxis initiative remains ambiguous.1 Although a diet high in sodium has …

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  • Competing interests None.