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Cochrane systematic review
Clonidine, SSRIs, SNRIs and gabapentin reduce hot flushes in women with a history of breast cancer; relaxation therapy may have a mild effect in the short term
  1. Deborah Fenlon
  1. Macmillan Survivorship Research Group, University of Southampton, Faculty of Health Sciences Southampton, UK
  1. Correspondence to Deborah Fenlon
    Macmillan Survivorship Research Group, Faculty of Health Sciences, University of Southampton, Highfield Campus, Southampton SO17 1BJ, UK; dfenlon{at}

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As treatments and early detection of breast cancer improve, the number of women affected by the consequences of treatment increases. Menopausal issues, such as hot flushes, may affect the majority of these women. Hot flushes may also be more troublesome in the context of breast cancer. At the same time women who have had breast cancer are advised not to take hormone therapies, which are the most effective treatment of this problem, and many are reluctant to take medications following a cancer diagnosis. Nursing staff are frequently called on to advice women in this position as to how to manage their hot flushes and therefore need to keep updated as to the latest evidence around effective and safe interventions. However, there is a large amount of literature on a wide range of potential interventions, and …

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  • Competing interests DF has received an honorarium from Roche for a presentation at the Champions for Change Conference.