Cardiovascular disease remains the leading cause of death, despite advances in treatment.1 In their systematic review, Cortes and colleagues examined the effect of an appealing intervention, early mobilisation, on mortality and re-infarction rates after acute myocardial infarction (AMI). The review is significant given the negative effects of bed rest and its continued prolonged use following AMI in many settings. The authors analysed data using relative risk with a 95% confidence interval. Their meta-analysis of 14 studies showed a 15% lower mortality risk in patients prescribed early mobilisation compared with the controls but no difference in re-infarction rates within 1 year of AMI. The authors concluded that there …