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A very low calorie diet plus lifestyle counselling improved mild obstructive sleep apnoea in overweight patients

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Does a very low calorie diet (VLCD) plus intensive lifestyle counselling improve mild obstructive sleep apnoea (OSA) in overweight patients?



randomised controlled trial (RCT).


unclear allocation concealment.


blinded (outcome assessors).

Follow-up period:

1 year.


Kuopio University Hospital, Kuopio, Finland.


81 patients 18–65 years of age (mean age 51 y, 65% men) who had a body mass index of 28–40 kg/m2 and an apnoea-hypopnoea index (AHI) of 5–15 events/hour. Exclusion criteria were active treatment for OSA, pregnancy, and chronic kidney, thyroid, or liver disease.


a VLCD (600–800 kcal/d) for 12 weeks plus intensive lifestyle counselling for 1 year (n = 40) or general oral and written …

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  • Sources of funding Juho Vainio Foundation; Yrjö Jahnsson Foundation; Jalmari and Rauha Ahokkaan Foundation; Finnish Anti-Tuberculosis Foundation.