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Can a clinical prediction rule based on preoperative factors accurately predict the development of delirium after cardiac surgery?
2 cohort studies: 1 for derivation and 1 for validation of the prediction model.
2 academic centres and 1 Veterans Administration hospital (derivation set), and 1 academic medical centre and 1 Veterans Administration hospital (validation set).
122 patients (mean age 75 y, 80% men) for the derivation set and 109 patients (mean age 73 y, 73% men) for the validation set. Patients were planning to have cardiac surgery (coronary artery bypass graft [CABG], mitral or aortic valve replacement or repair, or combined CABG-valve). Exclusion criteria included residence >60 miles from study centre, medical …
Source of funding: Harvard Older Americans Independence Center and National Institutes of Health.