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Intensive nutritional supplementation improved functional outcome after stroke

https://doi.org/10.1136/ebn.12.3.85

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    QUESTION

    Does an intensive nutritional supplement improve functional outcome in undernourished patients in a stroke rehabilitation unit?

    METHODS

    Design:

    randomised controlled trial.

    Allocation:

    concealed.

    Blinding:

    blinded (patients, healthcare providers, therapists, data collectors, and outcome assessors).

    Follow-up period:

    to discharge (mean 26 d).

    Setting:

    stroke rehabilitation unit in New York, USA.

    Patients:

    116 patients (mean age 74 y, 59% men) who had had a first stroke <4 weeks before admission to the unit, had ⩾2.5% weight loss within 2 weeks after the stroke, were medically stable, and were able to ingest food orally. Exclusion criteria were dementia, alcohol abuse, renal or liver disease, malabsorption, and terminal illness.

    Intervention:

    intensive nutritional supplement (240 calories, 11 g of protein) (n = 58) or standard nutritional supplement (127 calories, 5 g of protein) (n = 58), 120 …

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    Footnotes

    • Source of funding: Burke Medical Research Foundation and Novartis.