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Review: compression plus pharmacological prophylaxis reduces VTE more than monotherapy in high-risk patients

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S K Kakkos

Dr S K Kakkos, Henry Ford Hospital, Detroit, MI, USA;;


How does intermittent pneumatic leg compression (IPC) plus pharmacological prophylaxis compare with either monotherapy for preventing venous thromboembolism in high-risk patients?


Included studies compared ICP plus pharmacological prophylaxis with either therapy alone in patients at high risk of developing venous thromboembolism (including surgery and trauma patients). Studies evaluating intraoperative IPC were excluded. Outcomes were pulmonary embolism (PE) and deep venous thrombosis (DVT).


Medline, CINAHL, EMBASE/Excerpta Medica (all to present); Cochrane Peripheral Vascular …

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  • Source of funding: Scottish Government, UK.