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A nurse-delivered intervention was effective for depression in patients with cancer

https://doi.org/10.1136/ebn.12.1.17

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    M Sharpe

    Professor M Sharpe, University of Edinburgh, Edinburgh, UK; Michael.Sharpe@ed.ac.uk

    QUESTION

    What is the effectiveness of a complex, nurse-delivered intervention for treating major depression in patients with cancer?

    METHODS

    Design:

    randomised controlled trial (RCT) (Symptom Management Research Trials [SMaRT]).

    Allocation:

    {concealed}.*

    Blinding:

    blinded {data collectors, outcome assessors, data analysts, and safety committee}.*

    Follow-up period:

    12 months.

    Setting:

    a regional cancer centre in the UK.

    Patients:

    200 outpatients (mean age 57 y, 71% women) who had cancer with prognosis ⩾6 months and major depressive disorder (Symptom Checklist [SCL]-20 score ⩾1.75) for ⩾1 month. Exclusion criteria included epilepsy, concurrent intensive anticancer treatment (eg, frequent chemotherapy or radiotherapy), and receipt of specialist psychiatric care.

    Intervention:

    a nurse-delivered intervention plus usual care (n = 101) or usual care alone (n = 99). The intervention consisted …

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    Footnotes

    • Source of funding: Cancer Research UK.