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Review: dietary interventions, with or without exercise, promote weight loss more than advice alone

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M J Franz

Ms M J Franz, Nutrition Concepts by Franz Inc, Minneapolis, MN, USA;


What are the most effective interventions for weight loss in overweight and obese adults?


Data sources:

PubMed (1997 to Sep 2004) and reference lists.

Study selection and assessment:

English-language, randomised controlled trials (RCTs) that evaluated weight loss interventions in overweight or obese adults and had ⩾1 year follow-up. 80 RCTs (n = 26 455, mean age 23–69 y, 0–100% men) met the selection criteria. At baseline, mean weight was 77–131 kg and mean body mass index was 29–43 kg/m2. The interventions included advice only (28 RCTs), exercise (6 RCTs), diet (51 RCTs), diet plus exercise (17 RCTs), meal replacements (7 RCTs), very-low-energy diet (11 RCTs), orlistat (13 RCTs), and sibutramine (7 RCTs). No RCT on …

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  • Source of funding: no external funding.