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Treatment
A care management intervention improved depression after stroke

http://dx.doi.org/10.1136/ebn.10.4.117

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    Williams LS, Kroenke K, Bakas T, et al. Care management of poststroke depression: a randomized, controlled trial. Stroke 2007;38:998–1003.OpenUrlAbstract/FREE Full Text

    Q In patients with depression after stroke, does a care management intervention improve depression outcomes more than usual care?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    concealed.

    Embedded ImageBlinding:

    blinded (outcome assessor).

    Embedded ImageFollow-up period:

    12 weeks.

    Embedded ImageSetting:

    4 hospitals in Indianapolis, Indiana, USA.

    Embedded ImagePatients:

    188 patients ⩾18 years of age (mean age 60 y, 54% women) who had major (74%) or minor (26%) depression after ischaemic stroke (patients were identified at the time of stroke and screened for depression 1–2 mo later), no severe language or cognitive impairment, and a life expectancy ⩾6 months. Exclusion criteria included active psychosis, suicidality, substance abuse, use of a monoamine oxidase inhibitor, and pregnancy.

    Embedded ImageIntervention:

    the …

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    Footnotes

    • For correspondence: Dr L S Williams, Roudebush VA Medical Center, Indianapolis, IN, USA. linwilli{at}iupui.edu

    • Source of funding: National Institutes of Health/National Institute of Neurological Disorders and Stroke.