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2×2×2 factorial randomised controlled trial.
partially blinded (patients and healthcare providers were blinded to the drug intervention only).
Follow up period:
2 centres in Scotland, UK.
245 patients >18 years of age (mean age 70 y, 67% women) with clinical signs of venous disease and a venous leg ulcer ⩾1 cm in length and ⩾8 weeks in duration. Exclusion criteria included important arterial disease, …
For correspondence: Dr E A Nelson, University of Leeds, Leeds, UK.
Sources of funding: ConvaTec UK Ltd, Hoeschst Roussel Ltd UK, and Chief Scientist Office, Scotland.
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