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  • Moderate and high elastic compression hosiery did not differ statistically for recurrence of venous ulceration at 5 years

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Moderate and high elastic compression hosiery did not differ statistically for recurrence of venous ulceration at 5 years

https://doi.org/10.1136/ebn.10.2.55

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    Nelson EA, Harper DR, Prescott RJ, et al. Prevention of recurrence of venous ulceration: randomized controlled trial of class 2 and class 3 elastic compression. J Vasc Surg 2006;44:803–8.OpenUrlCrossRefPubMedWeb of Science

    Q What is the relative effectiveness of high compression (class 3) and moderate compression (class 2) hosiery for prevention of venous ulcer recurrence?

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    concealed (although concealment was potentially compromised in the allocation of 2 patients).

    Embedded ImageBlinding:

    blinded {data analysts}.*

    Embedded ImageFollow up period:

    5 years.

    Embedded ImageSetting:

    leg ulcer clinics at 2 hospitals in Scotland, UK.

    Embedded ImagePatients:

    300 patients (mean age 64 y, 58% women) with newly healed venous leg ulcers defined by clinical, Doppler, or duplex criteria. Exclusion criteria were diabetes, an ankle-brachial pressure index <0.8, or seropositive rheumatoid arthritis.

    Embedded ImageIntervention:

    151 patients were allocated to moderate compression (18–24 mm Hg at …

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    Footnotes

    • For correspondence: Dr E A Nelson, University of Leeds, Leeds, UK. e.a.nelson{at}leeds.ac.uk

    • Source of funding: Chief Scientist Office, Scotland.