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Moderate and high elastic compression hosiery did not differ statistically for recurrence of venous ulceration at 5 years

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Q What is the relative effectiveness of high compression (class 3) and moderate compression (class 2) hosiery for prevention of venous ulcer recurrence?


Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:

concealed (although concealment was potentially compromised in the allocation of 2 patients).

Embedded ImageBlinding:

blinded {data analysts}.*

Embedded ImageFollow up period:

5 years.

Embedded ImageSetting:

leg ulcer clinics at 2 hospitals in Scotland, UK.

Embedded ImagePatients:

300 patients (mean age 64 y, 58% women) with newly healed venous leg ulcers defined by clinical, Doppler, or duplex criteria. Exclusion criteria were diabetes, an ankle-brachial pressure index <0.8, or seropositive rheumatoid arthritis.

Embedded ImageIntervention:

151 patients were allocated to moderate compression (18–24 mm Hg at …

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  • For correspondence: Dr E A Nelson, University of Leeds, Leeds, UK. e.a.nelson{at}

  • Source of funding: Chief Scientist Office, Scotland.