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Review: support surfaces, nutritional supplements, and topical agents help prevent pressure ulcers

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Q What is the quality of evidence for various pressure ulcer prevention interventions?


Embedded ImageData sources:

Medline, EMBASE/Excerpta Medica, and CINAHL (to June 2006); Cochrane Library (Issue 1, 2006); UMI Proquest Digital Dissertations; ISI Web of Science; Cambridge Scientific Abstracts; and bibliographies of retrieved articles.

Embedded ImageStudy selection and assessment:

randomised controlled trials (RCTs) in any language that evaluated interventions for preventing pressure ulcers and reported objective, clinically relevant outcomes. 59 RCTs (n = 13 845) met the selection criteria. Quality assessment of individual studies was based on 6 elements from the CLEAR NPT checklist: randomisation procedure, allocation concealment, blinding of participants and outcome assessors, follow up, and intention to treat analysis.

Embedded ImageOutcomes:

incidence of …

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  • For correspondence: Dr M Reddy, Hebrew Rehabilitation Center, Boston, MA, USA. MahuriReddy{at}

  • Sources of funding: Canadian Institutes of Health Research and Ontario Ministry of Health.