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Q Do calcium supplements reduce loss of bone mineral density (BMD) and prevent fractures in healthy postmenopausal women?
METHODS
Design:
randomised, placebo controlled trial.
Allocation:
{concealed}.*
Blinding:
blinded {patients and clinicians}.*
Follow up period:
5 years (mean 4.5 y).
Setting:
{university medical centre}* in Auckland, New Zealand.
Participants:
1471 healthy postmenopausal women >55 years of age (mean age 74 y) who were not taking calcium or drugs for osteoporosis; had serum creatinine concentrations <2.3 mg/dl (0.2 mmol/l) and 25-hydroxyvitamin D >10 µg/l (25 nmol/l); and had lumbar spine BMD in the normal range for age.
Intervention:
elemental calcium (as citrate), 1 g …
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