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Causation
Review: good adherence to drug therapy is associated with reduced mortality

https://doi.org/10.1136/ebn.10.1.24

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    Simpson SH, Eurich DT, Majumdar SR, et al. A meta-analysis of the association between adherence to drug therapy and mortality. BMJ 2006;333:15.

    Q What is the relation between adherence to drug therapy and mortality?

    METHODS

    Embedded ImageData sources:

    AMED, CINAHL, Embase/Excerpta Medica, ERIC, HealthSTAR, Medline, PsycINFO, and Web of Science (all from inception to June 2005); and references from textbooks and review articles.

    Embedded ImageStudy selection and assessment:

    randomised controlled trials (RCTs) or observational studies in any language that evaluated the association between adherence to drug therapy and mortality, explained methods used to measure adherence, provided clear definitions of good adherence, and stratified patients into good and poor adherence groups. Studies that …

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    Footnotes

    • For correspondence: Dr S H Simpson, University of Alberta, Edmonton, Alberta, Canada. ssimpson{at}pharmacy.ualberta.ca

    • Source of funding: no external funding.