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Depression was associated with decreased survival for hospital patients who were seriously ill

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Question For hospital patients who are severely ill, is self reported depression associated with mortality after adjusting for functional status and severity of illness?


Cohort study with 4 year follow up (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments [SUPPORT]).


5 tertiary teaching hospitals in the US.


3529 patients (median age 63 y, median education level 12 y, 58% men, 78% white, 52% married) admitted to hospital with a serious illness. The projected 6 month survival for the group was 50%. Exclusion criteria were not speaking English; having AIDS, head trauma, or burns; being pregnant; <18 years old; expected hospital admission <72 hours; death …

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  • Source of funding: Robert Wood Johnson Foundation.

  • For correspondence: Dr M J Roach, Spinal Cord Research, Rammelkamp Building R230, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109–1998, USA. Fax +1 216 778 8782.