Article Text

Download PDFPDF
Low birth weight was associated with non-fatal coronary artery disease and stroke in nurses

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

OpenUrlAbstract/FREE Full Text


To determine if an association exists between birth weight and non-fatal cardiovascular disease in women who were nurses.


Cohort study of women in the Nurses' Health Study followed up every 2 years from 1976 to 1992.




70 297 women (mean age 42 y in 1976) born between 1921 and 1946, all registered nurses, who were free from coronary heart disease and stroke in 1976.

Assessment of risk factors

Women were grouped by their birth weight category: <2268 g (n=1392), 2268–2495 g (n=3549), >2495–3175 g (n=21 171), >3175–3856 g (n=31 216), >3856–4536 g (n=7723), or >4536 g (n=1638). 3608 women who were born prematurely were not included in the analysis. Postal questionnaires were used to gather data on past and current cardiovascular disease risk factors in 1976 and birth weight in 1992.

Main outcome measures

Data on non-fatal myocardial infarction …

View Full Text


  • Sources of funding: National Institutes of Health.

  • For article reprint: Dr J W Rich-Edwards, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, 126 Brookline Avenue, Suite 200, Boston, MA 02215, USA. Fax +1 617 421 2763.