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Review: compression treatment improves healing of venous leg ulcers

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To determine the effectiveness of compression treatment for venous leg ulcers using systematic review.

Data sources

Studies were identified using 19 bibliographic, citation, and research databases; searches of bibliographies of relevant papers; hand searches; and contact with manufacturers and authors.

Study selection

Studies were selected if they were randomised controlled trials (RCTs) which examined the effects of compression on the healing of venous leg ulcers.

Data extraction

Data were extracted (and checked by a second reviewer) on study inclusion and exclusion criteria, sample size, a priori sample size calculation, method of randomisation, comparability of treatment groups at baseline, blinded assessment of outcomes, use of appropriate outcome measures, and intention to treat analysis.

Main results

24 RCTs (6 unpublished) were included in the review. 6 …

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  • Source of funding: NHS Health Technology Assessment Programme.

  • For article reprint: Dr N Cullum, Department of Health Studies, The University of York, Heslington, York YO1 5DG, UK. Fax +44 (0)1904 435225.

  • * p value calculated from data in article.