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Telephone reminders improved compliance with a second dose of hepatitis B vaccine in high risk adults

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To determine whether telephone contact and postal reminders will increase compliance with a required second dose of hepatitis B vaccine in high risk adults.


Randomised controlled trial.


A sexually transmitted diseases clinic in Hamilton, Ontario, Canada.


256 self referred patients (mean age 26 y, 68% men) who were seronegative for hepatitis B virus chose to have the first of 2 doses of the vaccine. 136 adults did not return for their second dose of vaccine within 6 weeks and were enrolled in the study.


67 participants were allocated to receive enhanced follow up that included attempted telephone contact at least 3 times over 2 weeks by the clinic receptionist …

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