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Causation
Induced abortion did not increase the risk of breast cancer

https://doi.org/10.1136/ebn.1.1.21

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    Melbye M, Wohlfahrt J, Olsen Jh , Et AL. Induced abortion and the risk of breast cancer. N Engl J Med 1997 Jan 9; 336 : 81 –5. OpenUrlCrossRefPubMedWeb of Science

    Objective

    To determine whether an association exists between induced abortion and the risk of breast cancer.

    Design

    Cohort study of women followed up from 1968–92.

    Setting

    Population based study in Denmark.

    Participants

    All Danish women born from 1 April 1935 to 31 March 1978. In total, 1 529 512 women were included in the cohort.

    Assessment of risk factors

    Through a linkage with the National Registry of Induced Abortions, information on the number and dates of induced abortions was combined with information on the gestational age of each aborted fetus. The induced abortions included in this analysis were those that occurred between 1973 and 1992. Data on the obstetric history (age, …

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    Footnotes

    • Sources of funding: Danish Cancer Society; Danish National Research Foundation; U.S. Department of Defense.

    • For article reprint: Dr M Melbye, Department of Epidemiology Research, Danish Epidemiology Science Center, Statens Serum Institut, 5 Artillerivej, DK-2300 Copenhagen S, Denmark. Fax +45 32 68 31 65.

    • Adapted from an abstract published in ACP Journal Club 1997 Jul–Aug;127:18.